New treatments show promise against drug-resistant gonorrhea - 21 News Now, More Local News for Youngstown, Ohio -

New treatments show promise against drug-resistant gonorrhea

Updated:
© iStockphoto.com / Stepan Popov © iStockphoto.com / Stepan Popov
  • More NewsMore>>

  • Gender gap under Ohio governor nearly $10 an hour

    Gender gap under Ohio governor nearly $10 an hour

    DAYTON, Ohio (AP) - A newspaper investigation has found the average pay gap between men and women in the offices of four of Ohio's five elected statewide officials has grown to almost $10 an hour, as it's shrunk to under a dollar across the rest of state government.The Dayton Daily News reports (http://bit.ly/1jWcGS7 ) women working in Republican Gov. John Kasich's (KAY'-siks) office earn $9.81-an-hour less, on average, than men. That's the highest gender pay gap among statewide officeholders...More >>
    DAYTON, Ohio (AP) - A newspaper investigation has found the average pay gap between men and women in the offices of four of Ohio's five elected statewide officials has grown to almost $10 an hour, as it's shrunk to under a dollar across the rest of state government.The Dayton Daily News reports (http://bit.ly/1jWcGS7 ) women working in Republican Gov. John Kasich's (KAY'-siks) office earn $9.81-an-hour less, on average, than men. That's the highest gender pay gap among statewide officeholders...More >>
  • Ohioans encouraged to dispose of medications

    Ohioans encouraged to dispose of medications

    Monday, April 21 2014 10:12 AM EDT2014-04-21 14:12:20 GMT
    COLUMBUS, Ohio (AP) - The Ohio State Board of Pharmacy is encouraging Ohioans to participate in the U.S. Drug Enforcement Administration's "Drug Take-Back Day" next weekend. The event from 10 a.m. to 2 p.m. on Saturday allows people to drop off expired or unused prescription medications. The DEA is coordinating with local law enforcement agencies, which will accept the discarded controlled substances at various places around the state. Drop-off sites can be found here: http://1.usa.gov/PmDUp...More >>
    COLUMBUS, Ohio (AP) - The Ohio State Board of Pharmacy is encouraging Ohioans to participate in the U.S. Drug Enforcement Administration's "Drug Take-Back Day" next weekend. The event from 10 a.m. to 2 p.m. on Saturday allows people to drop off expired or unused prescription medications. The DEA is coordinating with local law enforcement agencies, which will accept the discarded controlled substances at various places around the state. Drop-off sites can be found here: http://1.usa.gov/PmDUp...More >>
  • Ohio theme parks building on record revenue

    Ohio theme parks building on record revenue

    Monday, April 21 2014 9:44 AM EDT2014-04-21 13:44:43 GMT
    MASON, Ohio (AP) - A new roller coaster at southwestern Ohio's Kings Island theme park is expected to contribute to another year of record revenue and attendance for its parent company. Sandusky-based Cedar Fair Entertainment Co. owns the park in Mason, as well as Cedar Point in northern Ohio. Net revenues last year reached $1.14 billion. A record-breaking 23.5 million visitors in 2013 attended Cedar Fair's 15 amusement and water parks in Ohio, eight other states and Canada. The Dayton Daily...More >>
    MASON, Ohio (AP) - A new roller coaster at southwestern Ohio's Kings Island theme park is expected to contribute to another year of record revenue and attendance for its parent company. Sandusky-based Cedar Fair Entertainment Co. owns the park in Mason, as well as Cedar Point in northern Ohio. Net revenues last year reached $1.14 billion. A record-breaking 23.5 million visitors in 2013 attended Cedar Fair's 15 amusement and water parks in Ohio, eight other states and Canada. The Dayton Daily...More >>

MONDAY, July 15 (HealthDay News) -- Two new promising treatments for gonorrhea may help fight the growth of drug-resistant strains of the sexually transmitted bacteria, according to a new U.S. government study.

The two antibiotic regimens use existing drugs in new combinations -- injectable gentamicin with azithromycin pills, or gemifloxacin pills with azithromycin pills.

Gonorrhea is one of the most common sexually transmitted diseases in the United States, with more than 800,000 new infections estimated to occur each year, according to the U.S. Centers for Disease Control and Prevention. Untreated, it can lead to problems with the prostate and testicles for men, and infertility in women. This is why its increasing antibiotic-resistance is a serious concern.

The U.S. government study included more than 400 men and women, aged 15 to 60, with untreated gonorrhea infection. The injectable gentamicin/oral azithromycin combination was 100 percent effective in curing genital gonorrhea infections, while the gemifloxacin/azithromycin pill combination was 99.5 percent effective. Both combinations cured 100 percent of infections of the throat and rectum, the researchers noted.

However, many patients in both arms of the study reported unpleasant side effects, including nausea, diarrhea and abdominal discomfort/pain or vomiting.

The study, scheduled for presentation this week at a meeting of the International Society for Sexually Transmitted Diseases Research in Vienna, Austria, was conducted by the CDC and the U.S. National Institutes of Health.

"These trial results are an exciting step in the right direction in the fight against drug-resistant gonorrhea," Dr. Gail Bolan, director of CDC's division of STD prevention, said in an agency news release. "But patients need more oral options with fewer side effects. It is imperative that researchers and pharmaceutical companies prioritize research to continue to identify new, effective, better-tolerated drugs and drug combinations."

Additional measures to stay ahead of resistant gonorrhea are critical, Dr. Anthony Fauci, director of NIH's National Institute of Allergy and Infectious Diseases, said in the news release. "For example, a point-of-care drug susceptibility test would help providers know -- at the time of diagnosis -- which treatment regimen will be most effective," he said.

"Progress toward a vaccine is urgently needed," Fauci added.

These findings do not change current gonorrhea treatment guidelines. The CDC recommends only one first-line treatment regimen: injectable ceftriaxone, in combination with one of two other antibiotics in pill form, either azithromycin or doxycycline. This therapy is highly effective in treating gonorrhea and causes limited side effects.

Ceftriaxone is in the same class of antibiotics as cefixime, a pill that has lost effectiveness against the sexually transmitted disease. Earlier this year, Canadian researchers reported on a study of nearly 300 people infected with Neisseria gonorrhoeae that found a treatment failure rate of nearly 7 percent in people treated with cefixime. Last August the CDC advised doctors to stop using cefixime to treat gonorrhea, and instead use injections of ceftriaxone.

However, doctors may consider using the treatments assessed in this new study as alternative options when ceftriaxone can't be used, such as in the case of a severe allergy, the CDC said. The agency says it will consider the study's findings for inclusion in future treatment guidelines.

To help prevent gonorrhea, people who are sexually active should use condoms consistently and correctly, and limit the number of sex partners, the CDC states.

The data and conclusions of research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. National Institute of Allergy and Infectious Diseases has more about gonorrhea.

Health News Copyright © 2013 HealthDay. All rights reserved.

*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.
  • Around the WebMore>>

  • GM boosting China production capacity to 5 million

    GM boosting China production capacity to 5 million

    Sunday, April 20 2014 10:52 AM EDT2014-04-20 14:52:53 GMT
    Sales of GM-brand vehicles in China should reach 5 million next year, and Cadillac sales will double to 100,000, the president of General Motors said Sunday.More >>
    The president of General Motors said Sunday that the company and local partners are boosting production capacity for GM-brand vehicles in China to 5 million.More >>
  • Ohio couple married 70 years die 15 hours apart

    Ohio couple married 70 years die 15 hours apart

    Sunday, April 20 2014 9:03 AM EDT2014-04-20 13:03:14 GMT
    NASHPORT, Ohio (AP) - An Ohio couple who held hands at breakfast every morning even after 70 years of marriage have died 15 hours apart.Helen Felumlee (FEHL'-uhm-lee) of Nashport in central Ohio died April 12. She was 92. Her husband, 91-year-old Kenneth Felumlee, died April 13.The couple's children say the two met as teenagers and had been inseparable since then.The Zanesville Times Recorder reports (http://ohne.ws/1in7erG) that the pair married Feb. 20, 1944, and raised eight children.Their...More >>
    NASHPORT, Ohio (AP) - An Ohio couple who held hands at breakfast every morning even after 70 years of marriage have died 15 hours apart.Helen Felumlee (FEHL'-uhm-lee) of Nashport in central Ohio died April 12. She was 92. Her husband, 91-year-old Kenneth Felumlee, died April 13.The couple's children say the two met as teenagers and had been inseparable since then.The Zanesville Times Recorder reports (http://ohne.ws/1in7erG) that the pair married Feb. 20, 1944, and raised eight children.Their...More >>
  • Easter Bunny train sparks New Jersey brush fires

    Easter Bunny train sparks New Jersey brush fires

    Sunday, April 20 2014 8:31 AM EDT2014-04-20 12:31:46 GMT
    POHATCONG TOWNSHIP, N.J. (AP) - A train carrying the Easter Bunny in northwestern New Jersey has ignited several small brush fires.The Express-Times newspaper in Easton, Pennsylvania, reports the fires occurred Saturday in Pohatcong Township and Phillipsburg. No major property damage is reported. A firefighter from the New Jersey state forest fire service fell and dislocated his hip.Huntington Volunteer Fire Company Chief Peter Pursell tells the newspaper the diesel en...More >>
    POHATCONG TOWNSHIP, N.J. (AP) - A train carrying the Easter Bunny in northwestern New Jersey has ignited several small brush fires.The Express-Times newspaper in Easton, Pennsylvania, reports the fires occurred Saturday in Pohatcong Township and Phillipsburg. No major property damage is reported. A firefighter from the New Jersey state forest fire service fell and dislocated his hip.Huntington Volunteer Fire Company Chief Peter Pursell tells the newspaper the diesel en...More >>
Powered by WorldNow
All content © Copyright 2000 - 2014 Worldnow and WFMJ. All Rights Reserved. For more information on this site, please read our Privacy Policy and Terms