Genetic syndrome may have links to Parkinson's disease - 21 News Now, More Local News for Youngstown, Ohio -

Genetic syndrome may have links to Parkinson's disease

Updated:
© iStockphoto.com / Ryan Pike © iStockphoto.com / Ryan Pike
  • More NewsMore>>

  • Gender gap under Ohio governor nearly $10 an hour

    Gender gap under Ohio governor nearly $10 an hour

    DAYTON, Ohio (AP) - A newspaper investigation has found the average pay gap between men and women in the offices of four of Ohio's five elected statewide officials has grown to almost $10 an hour, as it's shrunk to under a dollar across the rest of state government.The Dayton Daily News reports (http://bit.ly/1jWcGS7 ) women working in Republican Gov. John Kasich's (KAY'-siks) office earn $9.81-an-hour less, on average, than men. That's the highest gender pay gap among statewide officeholders...More >>
    DAYTON, Ohio (AP) - A newspaper investigation has found the average pay gap between men and women in the offices of four of Ohio's five elected statewide officials has grown to almost $10 an hour, as it's shrunk to under a dollar across the rest of state government.The Dayton Daily News reports (http://bit.ly/1jWcGS7 ) women working in Republican Gov. John Kasich's (KAY'-siks) office earn $9.81-an-hour less, on average, than men. That's the highest gender pay gap among statewide officeholders...More >>
  • Ohioans encouraged to dispose of medications

    Ohioans encouraged to dispose of medications

    Monday, April 21 2014 10:12 AM EDT2014-04-21 14:12:20 GMT
    COLUMBUS, Ohio (AP) - The Ohio State Board of Pharmacy is encouraging Ohioans to participate in the U.S. Drug Enforcement Administration's "Drug Take-Back Day" next weekend. The event from 10 a.m. to 2 p.m. on Saturday allows people to drop off expired or unused prescription medications. The DEA is coordinating with local law enforcement agencies, which will accept the discarded controlled substances at various places around the state. Drop-off sites can be found here: http://1.usa.gov/PmDUp...More >>
    COLUMBUS, Ohio (AP) - The Ohio State Board of Pharmacy is encouraging Ohioans to participate in the U.S. Drug Enforcement Administration's "Drug Take-Back Day" next weekend. The event from 10 a.m. to 2 p.m. on Saturday allows people to drop off expired or unused prescription medications. The DEA is coordinating with local law enforcement agencies, which will accept the discarded controlled substances at various places around the state. Drop-off sites can be found here: http://1.usa.gov/PmDUp...More >>
  • Ohio theme parks building on record revenue

    Ohio theme parks building on record revenue

    Monday, April 21 2014 9:44 AM EDT2014-04-21 13:44:43 GMT
    MASON, Ohio (AP) - A new roller coaster at southwestern Ohio's Kings Island theme park is expected to contribute to another year of record revenue and attendance for its parent company. Sandusky-based Cedar Fair Entertainment Co. owns the park in Mason, as well as Cedar Point in northern Ohio. Net revenues last year reached $1.14 billion. A record-breaking 23.5 million visitors in 2013 attended Cedar Fair's 15 amusement and water parks in Ohio, eight other states and Canada. The Dayton Daily...More >>
    MASON, Ohio (AP) - A new roller coaster at southwestern Ohio's Kings Island theme park is expected to contribute to another year of record revenue and attendance for its parent company. Sandusky-based Cedar Fair Entertainment Co. owns the park in Mason, as well as Cedar Point in northern Ohio. Net revenues last year reached $1.14 billion. A record-breaking 23.5 million visitors in 2013 attended Cedar Fair's 15 amusement and water parks in Ohio, eight other states and Canada. The Dayton Daily...More >>

MONDAY, Sept. 9 (HealthDay News) -- A genetic deletion may be linked to some cases of early onset Parkinson's disease, researchers say.

The investigators found that people aged 35 to 64 who were missing DNA on a specific part of chromosome 22 were about 90 times more likely to develop Parkinson's than people from the same age group in the general population.

People with this inherited genetic condition -- called 22q11.2 deletion syndrome -- have about 50 genes missing on chromosome 22. The condition occurs in about one in 2,000 to 4,000 people, and those with this genetic deletion may have birth defects (including heart defects), learning or speech difficulties, anxiety disorders, or schizophrenia.

Previously reported cases of patients with 22q11.2 deletion syndrome and Parkinson's disease symptoms have indicated that there may be a link between the two conditions, according to the researchers from the Center for Addiction and Mental Health and University Health Network in Toronto.

Dr. Anne Bassett, director of the Center for Addiction and Mental Health's Clinical Genetics Research Program, said 22q11.2 deletion syndromes has been studied in children and adolescents, but less is known about the syndrome in adults.

In addition, in some cases, Parkinson's disease in 22q11.2 deletion syndrome is associated with abnormal accumulations of a type of protein in the brain (called Lewy bodies), similar to what has been found in another genetic form of Parkinson's, the study authors said.

The findings, published online Sept. 9 in the journal JAMA Neurology, indicate that adults with 22q11.2 deletion syndrome should undergo routine checks for signs of Parkinson's disease.

"Most people with 22q11.2 [deletion syndrome] will not develop Parkinson's disease," Bassett, director of the University Health Network's Dalglish Family Hearts and Minds Clinic, the world's first clinic dedicated to adults with 22q11.2 deletion syndrome, said in a news release. "But it does occur at a rate higher than in the general population. We will now be on the lookout for this so we can provide the best care for patients."

Although the study found an association between 22q11.2 deletion syndrome and Parkinson's disease, it did not find a cause-and-effect relationship.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about Parkinson's disease.

Copyright © 2013 HealthDay. All rights reserved.

*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.
  • Around the WebMore>>

  • GM boosting China production capacity to 5 million

    GM boosting China production capacity to 5 million

    Sunday, April 20 2014 10:52 AM EDT2014-04-20 14:52:53 GMT
    Sales of GM-brand vehicles in China should reach 5 million next year, and Cadillac sales will double to 100,000, the president of General Motors said Sunday.More >>
    The president of General Motors said Sunday that the company and local partners are boosting production capacity for GM-brand vehicles in China to 5 million.More >>
  • Ohio couple married 70 years die 15 hours apart

    Ohio couple married 70 years die 15 hours apart

    Sunday, April 20 2014 9:03 AM EDT2014-04-20 13:03:14 GMT
    NASHPORT, Ohio (AP) - An Ohio couple who held hands at breakfast every morning even after 70 years of marriage have died 15 hours apart.Helen Felumlee (FEHL'-uhm-lee) of Nashport in central Ohio died April 12. She was 92. Her husband, 91-year-old Kenneth Felumlee, died April 13.The couple's children say the two met as teenagers and had been inseparable since then.The Zanesville Times Recorder reports (http://ohne.ws/1in7erG) that the pair married Feb. 20, 1944, and raised eight children.Their...More >>
    NASHPORT, Ohio (AP) - An Ohio couple who held hands at breakfast every morning even after 70 years of marriage have died 15 hours apart.Helen Felumlee (FEHL'-uhm-lee) of Nashport in central Ohio died April 12. She was 92. Her husband, 91-year-old Kenneth Felumlee, died April 13.The couple's children say the two met as teenagers and had been inseparable since then.The Zanesville Times Recorder reports (http://ohne.ws/1in7erG) that the pair married Feb. 20, 1944, and raised eight children.Their...More >>
  • Easter Bunny train sparks New Jersey brush fires

    Easter Bunny train sparks New Jersey brush fires

    Sunday, April 20 2014 8:31 AM EDT2014-04-20 12:31:46 GMT
    POHATCONG TOWNSHIP, N.J. (AP) - A train carrying the Easter Bunny in northwestern New Jersey has ignited several small brush fires.The Express-Times newspaper in Easton, Pennsylvania, reports the fires occurred Saturday in Pohatcong Township and Phillipsburg. No major property damage is reported. A firefighter from the New Jersey state forest fire service fell and dislocated his hip.Huntington Volunteer Fire Company Chief Peter Pursell tells the newspaper the diesel en...More >>
    POHATCONG TOWNSHIP, N.J. (AP) - A train carrying the Easter Bunny in northwestern New Jersey has ignited several small brush fires.The Express-Times newspaper in Easton, Pennsylvania, reports the fires occurred Saturday in Pohatcong Township and Phillipsburg. No major property damage is reported. A firefighter from the New Jersey state forest fire service fell and dislocated his hip.Huntington Volunteer Fire Company Chief Peter Pursell tells the newspaper the diesel en...More >>
Powered by WorldNow
All content © Copyright 2000 - 2014 Worldnow and WFMJ. All Rights Reserved. For more information on this site, please read our Privacy Policy and Terms