Extended hormone therapy doesn't help some prostate cancer - 21 News Now, More Local News for Youngstown, Ohio -

Extended hormone therapy doesn't help some prostate cancer patients

Updated:
© iStockphoto.com/ Lilli Day © iStockphoto.com/ Lilli Day

MONDAY, Sept. 23 (HealthDay News) -- For men with intermediate-risk prostate cancer, long-term hormone therapy after radiation therapy provides no survival advantages compared with short-term hormone therapy, according to a new study.

Hormone therapy is used to reduce the levels of male hormones (androgens) such as testosterone, which can stimulate the growth of prostate cancer cells.

Researchers examined data from 133 men with intermediate-risk prostate cancer who underwent either long-term hormone therapy (59 patients) or short-term hormone therapy (74 patients) after receiving external beam radiation therapy.

Ten-year overall survival was 61 percent in the short-term group and 65 percent in the long-term group, which is not a statistically significant difference. Disease-specific survival was 96 percent in both groups.

The study was scheduled for presentation Monday at the annual meeting of the American Society for Radiation Oncology, in Atlanta.

"Most clinicians have felt that 'more was better' when it came to blocking testosterone in prostate cancer patients, however, results for the specific endpoints we focused on, OS [overall survival] and DSS [disease-specific survival], indicate that this was clearly not the case," study lead author Dr. Amin Mirhadi, a radiation oncologist at Cedars-Sinai Medical Center in Los Angeles, said in a society news release.

"This data supports administering less treatment, which will result in fewer side effects and reduce patients' overall health care costs," Mirhadi added.

The data and conclusions of research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed journal.

More information

The Urology Care Foundation has more about hormone therapy for prostate cancer.

Copyright © 2013 HealthDay. All rights reserved.

*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.
  • Around the WebMore>>

  • 2 boaters found dead in Lake Erie; 2 more missing

    2 boaters found dead in Lake Erie; 2 more missing

    Thursday, April 17 2014 3:49 PM EDT2014-04-17 19:49:32 GMT
    TOLEDO, Ohio (AP) - Authorities say the bodies of two of four missing boaters in western Lake Erie have been recovered off the Ohio shoreline. Officials say they recovered the bodies of two females Thursday.More >>
    TOLEDO, Ohio (AP) - Authorities say the bodies of two of four missing boaters in western Lake Erie have been recovered off the Ohio shoreline. Officials say they recovered the bodies of two females Thursday.More >>
  • Boston Marathon organizers confident of safe race

    Boston Marathon organizers confident of safe race

    Police stepped up patrols near the Boston Marathon finish line after a masked man walked in the street with a rice cooker in his backpack only hours after the city marked the anniversary of last year's deadly...More >>
    The arrest of a man with a rice cooker in his backpack near the Boston Marathon finish line led police to step up patrols Wednesday, while organizers sought to assure the city and runners of a safe race next week.More >>
  • Low of 19 degrees in Toledo breaks 139-year record

    Low of 19 degrees in Toledo breaks 139-year record

    Wednesday, April 16 2014 6:34 PM EDT2014-04-16 22:34:39 GMT
    TOLEDO, Ohio (AP) - Winter temperatures are refusing to go away in northwestern Ohio. The thermometer dropped to 19 degrees in Toledo Wednesday morning, breaking a 139-year-old record for the same dateMore >>
    TOLEDO, Ohio (AP) - Winter temperatures are refusing to go away in northwestern Ohio. The thermometer dropped to 19 degrees in Toledo Wednesday morning, breaking a 139-year-old record for the same dateMore >>
Powered by WorldNow
All content © Copyright 2000 - 2014 Worldnow and WFMJ. All Rights Reserved. For more information on this site, please read our Privacy Policy and Terms