“The Ellen DeGeneres Show” is set to return for its 19th and final season on Monday, September 13th, filled with an audience full of fans attending an in-studio taping of the talk show for the very first time!

 Season 19 will kick off with longtime friends of the show, including “The Ellen DeGeneres Show’s” very first guest in 2003, Jennifer Aniston, who will be making her 23rd appearance, and fellow talk show host Jimmy Kimmel making his 20th appearance! Entrepreneur Kim Kardashian West will join DeGeneres for her first sit-down interview since wrapping the hit reality show, “Keeping Up with the Kardashians.” The hilarious Tiffany Haddish and Grammy Award-winning band Imagine Dragons will also help DeGeneres celebrate her almost two-decade tenure during premiere week.

Additional upcoming guests include Emmy Award-winning actress Melissa McCarthy, media mogul Sean “Diddy” Combs, star of the highly anticipated “Dear Evan Hansen” Julianne Moore, and Grammy Award-winning artist Melissa Etheridge.

“The Ellen DeGeneres Show” will welcome back a fully vaccinated live studio audience after hosting a virtual audience throughout most of the pandemic. After tickets to attend an in-studio taping of the talk show were made available on ellentube.com on August 16th, an overwhelming demand of 155,000+ requests flooded into the site within 24 hours from DeGeneres’ longtime fans to catch the trailblazing comedian host her iconic talk show one final time. The talk show will follow all health and safety protocols and COVID-19 guidelines.

DeGeneres will celebrate and thank her fans for their support and love throughout the years all season long. From checking in on extraordinary human interest stories that touched viewers worldwide, reminiscing about past celebrity appearances, to fun-filled surprises, DeGeneres is excited to walk down memory lane and continue creating more unforgettable moments this season.

 “The Ellen DeGeneres Show” airs weekdays at 2 p.m. on 21 WFMJ!