St. Clair Avenue has reopened after six fire departments battled a large fire at a business in St. Clair Township.

Calcutta, Liverpool Township, Negley, Highland Township and Glenmoore were on scene working to put out what remains of the fire.

The fire broke out at Mike Pusateri Excavating on the 16000 block of St. Clair Avenue around 4 p.m. according to fire dispatchers.

The road between McGuffey Drive and McCoy Avenue is still blocked off while crews continue to work.

At this time, there have been no reported injuries according to dispatchers.

Lt. Randy Schneider of the Calcutta Fire Department tells 21 News, two fire fighters suffered minor burns to the face and neck and were taken to the hospital.

He adds that during the process of putting the fire out propane and oxygen tanks exploded.

At one point, flames engulfed at least part of the building with massive plume of  smoke billowing to the sky.

The losses at the business is estimated to be around $750,000 according to Schneider, who referenced an estimate given by the owner of the business.

The cause of the fire is still being investigated, Schneider said.

This is a developing news story and will be updated as more information becomes available.